	US 12,214,021 B2
	Study on lactoferrin regulation of bone formation by means of vitamin D receptor
Huiyuan Guo, Beijing (CN); Yixuan Li, Beijing (CN); Hao Zhang, Beijing (CN); and Liang Zhao, Beijing (CN)
Assigned to CHINA AGRICULTURAL UNIVERSITY, Beijing (CN)
Appl. No. 17/059,565
Filed by CHINA AGRICULTURAL UNIVERSITY, Beijing (CN)
PCT Filed May 31, 2018, PCT No. PCT/CN2018/089332 § 371(c)(1), (2) Date Nov. 30, 2020, PCT Pub. No. WO2019/227421, PCT Pub. Date Dec. 5, 2019.
Prior Publication US 2021/0228689 A1, Jul. 29, 2021
Int. Cl. A61K 38/40 (2006.01); A23L 33/155 (2016.01); A23L 33/17 (2016.01); A61K 31/59 (2006.01); A61K 31/593 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01)

CPC A61K 38/40 (2013.01) [A61K 31/593 (2013.01); A61P 19/08 (2018.01)]

12 Claims

1. A method of treating Vitamin D (VD)-deficient osteoporosis, comprising administering to a patient in need thereof lactoferrin at a dose of 100 mg/kg Body Weight (BW),

wherein Vitamin D Receptor (VDR) gene and protein levels increase in the patient.