	US 12,214,005 B2
	Probiotic composition for prevention of bacterial vaginosis
Remco Kort, Amsterdam (NL); and Charlotte Van Der Veer, Blantyre (MW)
Assigned to NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO, DA's-Gravenhage (NL)
Filed by NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO, DA's-Gravenhage (NL)
Filed on Aug. 12, 2022, as Appl. No. 17/819,476.
Application 17/819,476 is a continuation of application No. 16/628,762, granted, now 11,446,343, previously published as PCT/NL2018/050479, filed on Jul. 12, 2018.
Claims priority of application No. 17181005 (EP), filed on Jul. 12, 2017.
Prior Publication US 2022/0378856 A1, Dec. 1, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/747 (2015.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01)

CPC A61K 35/747 (2013.01) [A61K 9/0014 (2013.01); A61K 9/20 (2013.01); A61K 9/48 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01)]

14 Claims

1. A method for the treatment or prevention of bacterial vaginosis, comprising topical administration of a mixture of strains of Lactobacillus crispatus, which mixture comprises strains that have a different carbohydrate degradation profile, comprising at least one strain of L. crispatus that is able to degrade glycogen, and at least one strain of L. crispatus that is able to degrade lactose.