US 12,213,955 B2
Compositions and methods for broad-spectrum antiviral therapy
Shuofeng Yuan, Shek Tong Tsui (HK); Fuk Woo Jasper Chan, Kowloon (HK); Hin Chu, Sai Ying Pun (HK); Johnson Yiu-Nam Lau, Houston, TX (US); and Kwok Yung Yuen, Pok Fu Lam (HK)
Assigned to VERSITECH LIMITED, Hong Kong (CN)
Appl. No. 16/757,312
Filed by VERSITECH LIMITED, Telegraph Bay (HK)
PCT Filed Oct. 16, 2018, PCT No. PCT/US2018/056138
§ 371(c)(1), (2) Date Apr. 17, 2020,
PCT Pub. No. WO2019/079339, PCT Pub. Date Apr. 25, 2019.
Claims priority of provisional application 62/573,933, filed on Oct. 18, 2017.
Prior Publication US 2020/0338032 A1, Oct. 29, 2020
Int. Cl. A61K 31/192 (2006.01); A61P 31/14 (2006.01); A61P 31/16 (2006.01); A61P 31/20 (2006.01)
CPC A61K 31/192 (2013.01) 14 Claims
 
1. A method of treating a viral infection, comprising: administering to a subject in need thereof, an effective amount of a compound AM580, having the structure:

OG Complex Work Unit Chemistry
wherein the viral infection is caused by a virus selected from the group consisting of MERS-CoV, SARS-CoV, Zika virus, Influenza A virus, Human Adenovirus, and Enterovirus.