US 12,213,942 B2
System for long time storage of pharmaceutical compositions at low temperatures
Rajendra Redkar, Clarks Summit, PA (US); Luce Sohier, Marly-le-Roi (FR); Alexander Humbertjean, Bad Krozingen (DE); Diana Löber, Bodenheim (DE); and Alexander Traxl, Lustenau (AT)
Assigned to SCHOTT Pharma AG & Co. KGaA, Mainz (DE); SCHOTT PHARMA SCHWEIZ AG, St. Gallen (DE); SCHOTT PHARMA USA, INC., Rye Brook, NY (US); and SCHOTT PHARMA FRANCE SAS, Colombes (FR)
Filed by SCHOTT Pharma AG & Co. KGaA, Mainz (DE); SCHOTT PHARMA SCHWEIZ AG, St. Gallen (CH); SCHOTT PHARMA USA, INC., Rye Brook, NY (US); and SCHOTT PHARMA FRANCE SAS, Colombes (FR)
Filed on Nov. 24, 2021, as Appl. No. 17/535,240.
Claims priority of provisional application 63/118,768, filed on Nov. 27, 2020.
Prior Publication US 2022/0168185 A1, Jun. 2, 2022
Int. Cl. A61J 1/14 (2023.01)
CPC A61J 1/1412 (2013.01) [A61J 1/1468 (2015.05)] 19 Claims
OG exemplary drawing
 
1. At least one system for storage of pharmaceutical compositions, the at least one system comprising:
a container comprising a neck and a crown, the crown comprising an upper crown surface;
a stopper comprising a flange and a plug, the flange comprising a lower flange surface and a flange height; and
a holding element configured to exert a force on the crown and the flange to form a horizontal contact area between the upper crown surface and the lower flange surface, the horizontal contact area having a size of 30 mm2 to 300 mm2 and the flange height being compressed at least partially in the horizontal contact area by 10% to 40%, wherein the horizontal contact area and the flange height are configured to maintain tightness at low temperatures, and wherein the container comprises an opening and the flange extends radially away from the opening past the upper crown surface.