US 12,213,721 B2
System, method and computer-accessible medium for catheter-based optical determination of met-myoglobin content for estimating radiofrequency ablated, chronic lesion formation in tissue
Christine Hendon, Riverdale, NY (US); Rajinder Singh-Moon, Mastic, NY (US); and Soo Young Park, Seoul (KR)
Assigned to THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, , NY (US)
Filed by THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US)
Filed on May 1, 2020, as Appl. No. 16/864,415.
Application 16/864,415 is a continuation in part of application No. 16/259,014, filed on Jan. 28, 2019, abandoned.
Application 16/864,415 is a continuation in part of application No. 15/758,639, abandoned, previously published as PCT/US2016/051293, filed on Sep. 12, 2016.
Claims priority of provisional application 62/968,629, filed on Jan. 31, 2020.
Claims priority of provisional application 62/622,267, filed on Jan. 26, 2018.
Claims priority of provisional application 62/217,518, filed on Sep. 11, 2015.
Prior Publication US 2020/0330145 A1, Oct. 22, 2020
Int. Cl. A61B 18/12 (2006.01); G16H 20/40 (2018.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1455 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); A61B 90/00 (2016.01); A61B 90/30 (2016.01)
CPC A61B 18/12 (2013.01) [G16H 20/40 (2018.01); A61B 5/14546 (2013.01); A61B 5/14552 (2013.01); A61B 5/7264 (2013.01); A61B 2017/00061 (2013.01); A61B 2018/00351 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00642 (2013.01); A61B 2090/061 (2016.02); A61B 2090/306 (2016.02)] 18 Claims
OG exemplary drawing
 
1. A method for determining at least one characteristic of at least one tissue, comprising:
ablating the at least one tissue;
illuminating, by a source, the at least one tissue during the ablation procedure;
receiving, by a detector, diffuse reflectance spectra in a wavelength range of 600 nm-1000 nm based on the illumination procedure; and
using a computer hardware arrangement, continuously determining the at least one characteristic based on the ablation and illumination procedures and the received diffuse reflectance spectra, wherein a separation distance between the source and the detector is between 0.8 mm and 1.7 mm.