US 11,887,319 B2
Systems and methods for reducing artifacts in oct angiography images
Homayoun Bagherinia, Oakland, CA (US); and Nathan D. Shemonski, San Francisco, CA (US)
Assigned to Carl Zeiss Meditec, Inc., Dublin, CA (US)
Filed by Carl Zeiss Meditec, Inc., Dublin, CA (US)
Filed on Mar. 25, 2020, as Appl. No. 16/830,121.
Application 16/830,121 is a continuation of application No. 16/522,192, filed on Jul. 25, 2019, granted, now 10,636,145.
Application 16/522,192 is a continuation of application No. 15/292,432, filed on Oct. 13, 2016, granted, now 10,402,965, issued on Sep. 3, 2019.
Claims priority of provisional application 62/254,672, filed on Nov. 12, 2015.
Prior Publication US 2020/0265580 A1, Aug. 20, 2020
Int. Cl. G06T 7/00 (2017.01); G06T 7/32 (2017.01); G06T 7/11 (2017.01)
CPC G06T 7/32 (2017.01) [G06T 7/0012 (2013.01); G06T 7/11 (2017.01); G06T 2207/10101 (2013.01); G06T 2207/30041 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method to reduce artifacts in optical coherence tomography (OCT) angiography images of a sample, the method comprising:
collecting, by an OCT system, a first set of OCT image data and a second set of OCT image data, wherein the first set of OCT image data and the second set of OCT image data contain data taken at approximately the same location and at different times on the sample;
splitting the first set of OCT image data and the second set of OCT image data into multiple pairs of regions of interest, each pair of regions of interest of each set corresponding to approximately the same location on the sample, wherein at least some of the pair of regions of interest being are at different depths within the sample;
generating a non-uniform depth-dependent correction map by calculating along the depth dimension one or more of a motion change or an intensity change between each pair of regions from the first set of OCT image data and the second set of OCT image data;
applying the depth-dependent correction map to the first set of OCT image data to correct one or more non-uniform changes along the depth dimension to define a depth-corrected first set of OCT image data, wherein the second set of OCT data remains not-depth-corrected by the depth-dependent correction map;
applying an OCT angiography processing technique on the depth-corrected first set of OCT image data and the not-depth-corrected second set of OCT image data to generate one or more OCT angiography images, the one or more OCT angiography images having reduced artifacts; and
storing or displaying the one or more OCT angiography images having reduced artifacts.