US 11,885,799 B2
Centrifuge including a magnetic element and method for centrifuging a reaction vessel unit
Zhaoqiang Wang, Yantai (CN); Wolfgang Mann, Neudrossenfeld (DE); and Wolfgang Heimberg, Ebersberg (DE)
Assigned to YANTAI AUSBIO LABORATORIES CO., LTD., Yantai (CN)
Filed by Yantai AusBio Laboratories Co., Ltd., Shandong (CN)
Filed on Jan. 19, 2021, as Appl. No. 17/151,999.
Application 17/151,999 is a continuation of application No. 16/250,092, filed on Jan. 17, 2019, granted, now 10,928,387.
Application 16/250,092 is a continuation of application No. 14/910,681, granted, now 10,338,063, issued on Jul. 2, 2019, previously published as PCT/EP2014/066947, filed on Aug. 6, 2014.
Claims priority of application No. 13179437 (EP), filed on Aug. 6, 2013.
Prior Publication US 2021/0270826 A1, Sep. 2, 2021
Int. Cl. G01N 33/543 (2006.01); B08B 3/10 (2006.01); B08B 9/00 (2006.01); B04B 5/04 (2006.01); G01N 35/02 (2006.01); B03C 1/01 (2006.01); B03C 1/28 (2006.01); B03C 1/30 (2006.01); B04B 7/04 (2006.01); B01L 9/00 (2006.01); B08B 3/04 (2006.01); B04B 11/04 (2006.01); G01N 35/04 (2006.01); B01L 3/00 (2006.01); B03C 1/00 (2006.01); B04B 15/02 (2006.01); B08B 3/02 (2006.01); B08B 3/06 (2006.01)
CPC G01N 33/54326 (2013.01) [B01L 9/523 (2013.01); B01L 13/02 (2019.08); B03C 1/002 (2013.01); B03C 1/01 (2013.01); B03C 1/288 (2013.01); B03C 1/30 (2013.01); B04B 5/0407 (2013.01); B04B 5/0414 (2013.01); B04B 7/04 (2013.01); B04B 15/02 (2013.01); B08B 3/02 (2013.01); B08B 3/04 (2013.01); B08B 3/06 (2013.01); B08B 3/10 (2013.01); B08B 9/00 (2013.01); G01N 33/54366 (2013.01); G01N 35/028 (2013.01); B01L 3/5085 (2013.01); B01L 2300/0829 (2013.01); B01L 2400/0409 (2013.01); B03C 2201/18 (2013.01); B03C 2201/26 (2013.01); B04B 2011/046 (2013.01); G01N 2035/0437 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A centrifuge for washing magnetic beads in a plurality of reaction vessels of a reaction vessel unit in which the plurality of reaction vessels are arranged in a two-dimensional array and in which each reaction vessel includes at least one opening, the centrifuge comprising:
a housing;
a rotor disposed within the housing, the rotor being configured to rotate around a horizontal rotation axis and to hold the reaction vessel unit with respective openings of the plurality of reaction vessels directed radially outwardly relative to the horizontal rotation axis of the rotor;
a motor coupled with the rotor to rotate the rotor around the horizontal rotation axis of the rotor; and
one or more magnetic elements arranged in the rotor to apply a magnetic field to the plurality of reaction vessels in the two-dimensional array of reaction vessels of the reaction vessel unit that the rotor is configured to hold;
wherein the motor is configured to rotate the rotor around the horizontal rotation axis at a speed of rotation sufficient to wash, by centrifugation, the magnetic beads in the plurality of reaction vessels of the reaction vessel unit that the rotor is configured to hold; and
wherein the magnetic field applied by the one or more magnetic elements is sufficient to retain during centrifugation the magnetic beads in the plurality of reaction vessels of the reaction vessel unit that the rotor is configured to hold with respective openings of the plurality of reaction vessels directed radially outwardly relative to the horizontal rotation axis of the rotor.