US 11,885,733 B2
White blood cell population dynamics
John M. Higgins, Cambridge, MA (US); and Anwesha Chaudhury, Boston, MA (US)
Assigned to The General Hospital Corporation, Boston, MA (US)
Filed by The General Hospital Corporation, Boston, MA (US)
Filed on Mar. 4, 2022, as Appl. No. 17/687,270.
Application 17/687,270 is a division of application No. 16/091,576, granted, now 11,293,852, previously published as PCT/US2017/026695, filed on Apr. 7, 2017.
Claims priority of provisional application 62/466,590, filed on Mar. 3, 2017.
Claims priority of provisional application 62/437,468, filed on Dec. 21, 2016.
Claims priority of provisional application 62/319,370, filed on Apr. 7, 2016.
Prior Publication US 2022/0187190 A1, Jun. 16, 2022
Int. Cl. G01N 15/14 (2006.01); G16Z 99/00 (2019.01); G01N 33/49 (2006.01); G01N 15/00 (2006.01); G01N 15/10 (2006.01)
CPC G01N 15/1459 (2013.01) [G16Z 99/00 (2019.02); G01N 33/49 (2013.01); G01N 2015/008 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1402 (2013.01); G01N 2015/1488 (2013.01); G01N 2015/1493 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system comprising a processing device, and one or more computer-readable non-transitory media storing instructions that are executable by the processing device, and upon execution cause the processing device to perform operations comprising:
estimating a value of a parameter indicative of white blood cell (WBC) population dynamics of a patient based on data indicative of a property value of each WBC in a sample of white blood cells (WBCs) of the patient, the property value of a WBC being indicative of an age of the WBC; and
providing information for treatment or diagnosis of a condition of the patient associated with an inflammatory or immune system response based on the parameter.