	US 11,884,958 B2
	Assessing and treating functional gastrointestinal disorders
Purna C. Kashyap, Rochester, MN (US)
Assigned to Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed by Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed on Apr. 24, 2020, as Appl. No. 16/857,965.
Claims priority of provisional application 62/840,867, filed on Apr. 30, 2019.
Prior Publication US 2020/0399673 A1, Dec. 24, 2020
Int. Cl. C12Q 1/06 (2006.01); C09D 175/08 (2006.01)

CPC C12Q 1/06 (2013.01) [C09D 175/08 (2013.01)]

6 Claims

1. A method for treating a mammal having a functional gastrointestinal disorder (FGID) using a targeted treatment approach, wherein said method comprises:

(a) identifying said mammal as having a small intestinal microbiome (i) comprising two or more microbes selected from group A consisting of Anaeroglobus species, Erwinia species, Escherichia species, Staphylococcus species, Scardovia species, Bifidobacterium species, Lactobacillus species, Olsenella species, Slackia species, and Shuttleworthia species; and (ii) comprising reduced levels of two or more microbes selected from group B consisting of Lachnoanaerobaculum species, Prevotella species, Leptotrichia species, Catonella species, Gemella species, Neisseria species, Haemophilus species, and Streptococcus species; and

(b) administering a probiotic to said mammal, wherein said probiotic comprises one or more of said microbes selected from said group B that were identified as having said reduced levels in said step (a).