US 11,884,743 B2
Preparation and application of an intact recombinant antibody specific to clothianidin based on the identified variable region sequence
Yirong Guo, Zhejiang (CN); Yunyun Chang, Zhejiang (CN); Rubing Zou, Zhejiang (CN); Ying Zhao, Zhejiang (CN); Shasha Jiao, Zhejiang (CN); and Guonian Zhu, Zhejiang (CN)
Assigned to Zhejiang University, Zhejiang (CN)
Appl. No. 17/921,355
Filed by Zhejiang University, Zhejiang (CN)
PCT Filed Oct. 16, 2020, PCT No. PCT/CN2020/121649
§ 371(c)(1), (2) Date Oct. 26, 2022,
PCT Pub. No. WO2021/218053, PCT Pub. Date Nov. 4, 2021.
Claims priority of application No. 202010336548.9 (CN), filed on Apr. 26, 2020.
Prior Publication US 2023/0174676 A1, Jun. 8, 2023
Int. Cl. C07K 16/44 (2006.01); G01N 33/543 (2006.01)
CPC C07K 16/44 (2013.01) [G01N 33/54387 (2021.08); C07K 2317/56 (2013.01); C07K 2317/64 (2013.01); G01N 2430/10 (2013.01)] 7 Claims
 
1. An intact recombinant antibody against clothianidin, comprising a heavy chain constant region, a heavy chain variable region, a light chain constant region, and a light chain variable region, wherein the amino acid sequence of the heavy chain variable region comprises SEQ ID NO: 2, and the amino acid sequence of the light chain variable region comprises SEQ ID NO: 4.