CPC C07J 9/00 (2013.01) [A61K 31/57 (2013.01); C07J 17/00 (2013.01); C07J 43/003 (2013.01)] | 27 Claims |
1. A compound of Formula (I-B):
or a pharmaceutically acceptable salt thereof, wherein:
R1 is hydrogen or substituted or unsubstituted C1-6 alkyl;
R5 is absent or hydrogen;
Z is —C(RA)2—, —NRB—, —O—, or —S—;
X is halogen, substituted or unsubstituted C1-6 alkyl, or —ORC;
RA is hydrogen, halogen, or substituted or unsubstituted C1-6 alkyl;
RB is hydrogen, substituted or unsubstituted C1-6 alkyl, —C(O)RC, —C(O)ORC, —C(O)N(RD)2, or —S(O)2RC;
RC is hydrogen or substituted or unsubstituted C1-6 alkyl;
each RD is independently hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
m is an integer selected from 1, 2, and 3;
n is an integer selected from 1, 2, and 3;
p is an integer selected from 0, 1, 2, 3, 4, and 5; and
represents a single or double bond, wherein when one is a double bond, then the other is a single bond and R5 is absent.
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