US 11,884,695 B2
Heavy vitamin B12 derivatives
Peter Anderson, Orange (AU)
Assigned to CHARLES STURT UNIVERSITY, Wagga Wagga (AU)
Filed by CHARLES STURT UNIVERSITY, Wagga Wagga (AU)
Filed on Oct. 11, 2022, as Appl. No. 18/045,596.
Application 18/045,596 is a continuation of application No. 17/128,511, filed on Dec. 21, 2020, granted, now 11,597,747.
Application 17/128,511 is a continuation of application No. 15/546,628, granted, now 10,899,789, issued on Jan. 26, 2021, previously published as PCT/AU2015/050027, filed on Jan. 28, 2015.
Prior Publication US 2023/0183287 A1, Jun. 15, 2023
Int. Cl. C07H 23/00 (2006.01); G01N 33/82 (2006.01); G01N 30/72 (2006.01)
CPC C07H 23/00 (2013.01) [G01N 30/7233 (2013.01); G01N 33/82 (2013.01)] 20 Claims
 
1. A heavy vitamin B12 having a mass shift of at least +8 over unlabelled vitamin B12, wherein the heavy vitamin B12 comprises eight or nine 13C atoms and the eight or nine 13C atoms are located in the dimethylbenzimidazole moiety of the vitamin.