US 11,884,640 B2
Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom
Chun-Yu Lin, Yangmei (TW); Tzyh-Mann Wei, Yangmei (TW); and Shih-Yi Wei, Yangmei (TW)
Assigned to CHIROGATE INTERNATIONAL INC., Yangmei (TW)
Filed by CHIROGATE INTERNATIONAL INC., Yangmei (TW)
Filed on Jun. 2, 2021, as Appl. No. 17/336,865.
Prior Publication US 2023/0002339 A1, Jan. 5, 2023
Int. Cl. C07D 307/93 (2006.01); C07C 45/65 (2006.01); C07C 49/573 (2006.01); C07C 67/24 (2006.01); C07C 67/317 (2006.01); C07C 69/157 (2006.01); C07C 69/734 (2006.01); C07D 307/42 (2006.01); C07F 7/18 (2006.01); C12P 7/38 (2006.01)
CPC C07D 307/93 (2013.01) [C07C 45/65 (2013.01); C07C 49/573 (2013.01); C07C 67/24 (2013.01); C07C 67/317 (2013.01); C07C 69/157 (2013.01); C07C 69/734 (2013.01); C07D 307/42 (2013.01); C07F 7/1892 (2013.01); C12P 7/38 (2013.01); C07C 2601/08 (2017.05); C07C 2601/10 (2017.05); C07C 2601/16 (2017.05)] 4 Claims
 
1. An optically enriched compound of Formula 4a″:

OG Complex Work Unit Chemistry
wherein Y is Cl, Br, or I.