US 11,883,815 B2
Apparatus for sterile transfer of material between a container and an isolator
Hans-Werner Mumm, Soerup (DE)
Assigned to ATEC PHARMATECHNIK GMBH, Soerup (DE)
Appl. No. 17/609,412
Filed by ATEC PHARMATECHNIK GMBH, Soerup (DE)
PCT Filed Apr. 9, 2020, PCT No. PCT/EP2020/060234
§ 371(c)(1), (2) Date Nov. 8, 2021,
PCT Pub. No. WO2020/229067, PCT Pub. Date Nov. 19, 2020.
Claims priority of application No. 10 2019 003 317 .5 (DE), filed on May 10, 2019.
Prior Publication US 2022/0250050 A1, Aug. 11, 2022
Int. Cl. B01L 1/02 (2006.01); B01L 3/00 (2006.01); B65D 45/34 (2006.01); F16J 13/24 (2006.01)
CPC B01L 1/02 (2013.01) [B01L 3/50825 (2013.01); B65D 45/345 (2013.01); F16J 13/24 (2013.01); B01L 2200/026 (2013.01); B01L 2200/141 (2013.01); B01L 2300/04 (2013.01)] 14 Claims
OG exemplary drawing
 
1. An apparatus for a sterile transfer of a material between a container and an isolator, wherein,
the container comprises,
a container opening,
a container flange which is configured to surround the container opening, and
a container cover which is configured to close off the container opening and to be removable from the container flange, and
the isolator comprises,
a port opening,
a port flange which is configured to surround the port opening,
a port door which is configured to close off the port opening, and
an actuation mechanism which is configured to move between a closed position and an open position so as to open and close the port door,
wherein,
the container flange is configured to be releasably connected to the port flange, and
the container cover is configured to be releasably connected to the port door, the apparatus comprising at least one of,
a first safety device which is configured to lock the actuation mechanism in the closed position and to unlock the actuation mechanism when the port door abuts against the container cover,
a second safety device which is configured to lock the actuation mechanism in the closed position and unlock the actuation mechanism when the container flange is correctly connected to the port flange,
a third safety device which is configured to lock the container flange connected to the port flange when the actuation mechanism leaves the closed position,
a fourth safety device which is configured to block a return of the actuation mechanism from the open position to the closed position when the port door is open, and
a fifth safety device which is configured to lock the actuation mechanism if the container flange is not correctly connected to the port flange between the unlocking of the actuation mechanism by the second safety device and the locking of the container flange by the third safety device,
wherein,
at least one of the second safety device, the third safety device, and the fourth safety device comprises two magnetic elements which are configured to be movable relative to each another,
at least one closed wall without a through-opening is arranged between the two magnetic elements, and
the two magnetic elements are configured to mutually attract or to mutually repel through the at least one closed wall either in a lock position or in an unlock position of the at least one of the second safety device, the third safety device and the fourth safety device, as the case might be.