US 11,883,575 B2
System and method for selecting and culturing cells
Christopher J. Wegener, Libertyville, IL (US); Bret M. Olson, Chicago, IL (US); Alaina Schlinker, Chicago, IL (US); Steven Binninger, Evanston, IL (US); Avnie A. Kadakia, Chicago, IL (US); Kyle Thompson, Vernon Hills, IL (US); Kyle Wolok, Chicago, IL (US); and Melanie Hamilton, Glenview, IL (US)
Assigned to Fenwal, Inc., Lake Zurich, IL (US)
Filed by Fenwal, Inc., Lake Zurich, IL (US)
Filed on Sep. 19, 2019, as Appl. No. 16/576,484.
Application 16/576,484 is a continuation of application No. 15/498,918, filed on Apr. 27, 2017, granted, now 10,449,283.
Claims priority of provisional application 62/473,021, filed on Mar. 17, 2017.
Claims priority of provisional application 62/437,243, filed on Dec. 21, 2016.
Claims priority of provisional application 62/329,636, filed on Apr. 29, 2016.
Prior Publication US 2020/0009309 A1, Jan. 9, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 1/26 (2006.01); A61M 1/36 (2006.01); C12M 1/00 (2006.01); C12M 1/26 (2006.01); C12M 1/36 (2006.01); G01N 33/543 (2006.01)
CPC A61M 1/262 (2014.02) [A61M 1/265 (2014.02); A61M 1/362 (2014.02); A61M 1/3618 (2014.02); C12M 23/28 (2013.01); C12M 29/14 (2013.01); C12M 33/14 (2013.01); C12M 41/48 (2013.01); C12M 47/04 (2013.01); G01N 33/54326 (2013.01); G01N 33/54366 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A cell processing system comprising:
at least one processor connectable to a source container filled with a biological fluid, the at least one processor comprising:
a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet;
at least a first container and a second container selectively connected to the first outlet; and
a magnet; and
a controller coupled to the at least one processor and configured:
to operate the spinning membrane to receive biological fluid from the source container and to direct the target cells to the first container;
to pause operation of the processor to permit magnetic particles to be associated with the target cells in the first container;
to operate the spinning membrane to receive the contents of the first container with the magnet applied to the target cells associated with the magnetic particles in the first container;
to remove and/or deactivate the magnet applied to the target cells associated with the magnetic particles in the first container;
to transfer the target cells to the second container after removal and/or deactivation of the magnet; and
to prompt an operator to remove the second container after the target cells are transferred to the second container.