US 11,883,543 B2
Systems and methods for photoactivation of a biological fluid
Lan T. Nguyen, Vernon Hills, IL (US); Angela N. Carlson, Arlington Heights, IL (US); Katherine N. Radwanski, Highland Park, IL (US); Greg Coultas, Chicago, IL (US); Yamen Alshawaf, Burr Ridge, IL (US); and Kevin Schalte, Crystal Lake, IL (US)
Assigned to Fenwal, Inc., Lake Zurich, IL (US)
Filed by Fenwal, Inc., Lake Zurich, IL (US)
Filed on Mar. 30, 2020, as Appl. No. 16/834,012.
Claims priority of provisional application 62/834,467, filed on Apr. 16, 2019.
Prior Publication US 2020/0330628 A1, Oct. 22, 2020
Int. Cl. A61L 2/00 (2006.01); A61M 1/36 (2006.01); A61L 2/24 (2006.01)
CPC A61L 2/0052 (2013.01) [A61L 2/0047 (2013.01); A61L 2/24 (2013.01); A61M 1/3622 (2022.05); A61L 2202/14 (2013.01); A61L 2202/22 (2013.01)] 5 Claims
OG exemplary drawing
 
1. A device for treating a biological fluid with light comprising:
a) a housing defining an irradiation chamber;
b) a tray having a first side and a second side located interior of the irradiation chamber for supporting on the first side a container of the biological fluid;
c) a first array of multiple light sources mounted in the housing on the first side of the tray;
d) first light energy sensors mounted in the housing on the first side of the tray in association with each of the multiple light sources in the first array;
e) a second light energy sensor mounted in the housing on the second side of the tray; and
f) a programmable controller having an operator input for receiving a target light dose for the biological fluid and configured to automatically: i) activate the first array of multiple light sources, ii) measure a first light intensity with the first light energy sensors, iii) measure a second light intensity with the second light energy sensor, iv) compare the first light intensity to the second light intensity to determine an attenuation factor, v) apply the attenuation factor to the first light intensity to determine a time to achieve the target light dose, vi) adjust the time to achieve the target light dose based on the first light intensity and attenuation factor, and vii) deactivate the first array of multiple light sources after the time to achieve the target light dose has elapsed.