US 11,883,529 B2
Methods of administering anti-epilepsy agents and transport inhibitors to a subject
Brian A. Duclos, Minneapolis, MN (US)
Assigned to Medtronic, Inc., Minneapolis, MN (US)
Filed by Medtronic, Inc., Minneapolis, MN (US)
Filed on Aug. 5, 2021, as Appl. No. 17/394,588.
Claims priority of provisional application 63/071,617, filed on Aug. 28, 2020.
Prior Publication US 2022/0062171 A1, Mar. 3, 2022
Int. Cl. A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/195 (2006.01)
CPC A61K 9/0085 (2013.01) [A61K 9/08 (2013.01); A61K 31/195 (2013.01)] 20 Claims
 
1. A method for affecting epilepsy in a subject, the method comprising:
administering a liquid formulation comprising an antiepileptic compound to a cerebrospinal fluid (CSF)-containing intrathecal space of the subject; and
administering a liquid formulation comprising a multidrug resistance protein (MRP) inhibitor compound to an CSF-containing intrathecal space of the subject.