CPC A61K 9/0019 (2013.01) [A61K 9/0051 (2013.01); A61K 31/4439 (2013.01); A61K 47/34 (2013.01)] | 13 Claims |
1. An implant comprising:
axitinib; and
a bioerodible polyester polymer blend comprising at least two polymers, wherein the bioerodible polyester polymer blend comprises an acid or ester end group polylactic acid (PLA) and an acid or ester end group poly-D,L-lactide-co-glycolide (PLGA), and wherein at least one of the two polymers comprises an ester end group,
wherein the PLA is selected from polymers with an inherent viscosity selected from between about 0.16 dl/g to about 0.35 dl/g as measured in 0.1% chloroform (25 ° C., Ubbelohde) size 0 capillary viscometer, and
wherein the axitinib is present in the implant in an amount selected from a range of between about 5 and about 80 percent (w/w).
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