US 11,883,505 B2
Anticancer drug-containing plant virus particles
Nicole F. Steinmetz, San Diego, CA (US); Stephen J. Lippard, Cambridge, MA (US); Anna Czapar, Cleveland, OH (US); and Yaorong Zheng, Cambridge, MA (US)
Assigned to CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US); and MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US)
Filed by CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US); and MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US)
Filed on Apr. 21, 2020, as Appl. No. 16/854,444.
Application 16/854,444 is a continuation of application No. 15/741,017, granted, now 10,624,975, previously published as PCT/US2016/039961, filed on Jun. 29, 2016.
Claims priority of provisional application 62/201,227, filed on Aug. 5, 2015.
Claims priority of provisional application 62/185,881, filed on Jun. 29, 2015.
Prior Publication US 2020/0246482 A1, Aug. 6, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61P 35/00 (2006.01); A61K 9/19 (2006.01); A61K 31/555 (2006.01); A61K 39/12 (2006.01); A61K 47/69 (2017.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 39/00 (2006.01)
CPC A61K 47/6901 (2017.08) [A61K 9/0019 (2013.01); A61K 9/5184 (2013.01); A61K 31/555 (2013.01); A61K 39/12 (2013.01); A61P 35/00 (2018.01); A61K 2039/585 (2013.01); C12N 2750/12022 (2013.01); C12N 2750/12023 (2013.01); C12N 2770/00034 (2013.01); C12N 2770/00042 (2013.01); C12N 2770/32022 (2013.01); C12N 2770/32023 (2013.01)] 12 Claims
 
1. An anticancer virus particle, comprising a tobacco mosaic virus particle and a cationic platinum-based anticancer agent and any carrier for the agent are non-covalently encapsulated within an interior channel of the tobacco mosaic virus particle.