Billy M. Hargis, Fayetteville, AR (US); Neil R. Pumford, Bentonville, AR (US); Marion Morgan, Springdale, AR (US); Srichaitanya Shivaramaiah, Bangalore (IN); Guillermo Tellez-Isaias, Fayetteville, AR (US); and Amanda Wolfenden, Pea Ridge, AR (US)
Assigned to THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, Little Rock, AR (US)
Filed by THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, Little Rock, AR (US)
Filed on Sep. 15, 2020, as Appl. No. 17/021,345.
Application 17/021,345 is a continuation of application No. 16/379,535, filed on Apr. 9, 2019, granted, now 10,780,162, issued on Sep. 22, 2020.
Application 16/379,535 is a continuation of application No. 15/363,281, filed on Nov. 29, 2016, granted, now 10,258,688, issued on Apr. 16, 2019.
Application 15/363,281 is a continuation of application No. 14/439,536, abandoned, previously published as PCT/US2013/067212, filed on Oct. 29, 2013.
Claims priority of provisional application 61/719,713, filed on Oct. 29, 2012.
Prior Publication US 2021/0000947 A1, Jan. 7, 2021
1. A method of enhancing the immune response to a vaccine in a mammalian subject or a poultry subject comprising administering to said subject an effective amount of an adjuvant composition comprising a carbohydrate linked to chitosan to form a Schiff base, wherein the carbohydrate is an open ring mannose moiety and an effective amount of a vaccine composition comprising an antigen, wherein the difference in administration time for the administration of the adjuvant composition and the administration of the vaccine composition is between 1 hour and 25 days.