	US 11,883,471 B2
	Enhancing health in mammals using telomerase reverse transcriptase gene therapy
William H. Andrews, Reno, NV (US); Lancer K. Brown, Sparks, NV (US); Hamid Mohammadpour, Reno, NV (US); and Laura A. Briggs, Reno, NV (US)
Assigned to Sierra Sciences, LLC, Reno, NV (US)
Filed by Sierra Sciences, LLC, Reno, NV (US)
Filed on May 26, 2021, as Appl. No. 17/331,178.
Application 17/331,178 is a continuation of application No. 16/803,006, filed on Feb. 27, 2020, granted, now 11,052,134.
Application 16/803,006 is a continuation of application No. 15/220,250, filed on Jul. 26, 2016, granted, now 10,610,574, issued on Apr. 7, 2020.
Application 15/220,250 is a continuation of application No. 14/655,140, granted, now 9,453,209, issued on Sep. 27, 2016, previously published as PCT/US2013/077619, filed on Dec. 23, 2013.
Claims priority of provisional application 61/746,438, filed on Dec. 27, 2012.
Prior Publication US 2021/0361751 A1, Nov. 25, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07H 21/04 (2006.01); A61K 38/45 (2006.01); C12N 9/12 (2006.01); C12N 7/00 (2006.01); A61K 48/00 (2006.01); A61K 38/00 (2006.01)

CPC A61K 38/45 (2013.01) [A61K 48/00 (2013.01); A61K 48/005 (2013.01); A61K 48/0066 (2013.01); C12N 7/00 (2013.01); C12N 9/1276 (2013.01); C12Y 207/07049 (2013.01); A61K 38/00 (2013.01); C12N 2710/10341 (2013.01); C12N 2740/15041 (2013.01); C12N 2750/14143 (2013.01)]

17 Claims

1. A method of treating an age-related disorder in a subject comprising administering to the subject a nucleic acid vector comprising a coding sequence for telomerase reverse transcriptase (TERT), wherein the coding sequence is for human TERT and the vector expresses functional human TERT when present in a human cell.