US 11,883,407 B2
Medicament for the treatment of chronic cough
Ryuta Tamano, Osaka (JP); Erika Kasai, Osaka (JP); Sayaka Miyazaki, Osaka (JP); and Katsue Magari, Osaka (JP)
Assigned to SHIONOGI & CO., LTD., Osaka (JP)
Appl. No. 17/281,741
Filed by Shionogi & Co., Ltd., Osaka (JP)
PCT Filed Oct. 4, 2019, PCT No. PCT/JP2019/039275
§ 371(c)(1), (2) Date Mar. 31, 2021,
PCT Pub. No. WO2020/071530, PCT Pub. Date Apr. 9, 2020.
Claims priority of application No. 2018-189791 (JP), filed on Oct. 5, 2018; application No. 2019-044943 (JP), filed on Mar. 12, 2019; and application No. 2019-173841 (JP), filed on Sep. 25, 2019.
Prior Publication US 2021/0393640 A1, Dec. 23, 2021
Int. Cl. A61K 31/53 (2006.01); A61P 11/14 (2006.01)
CPC A61K 31/53 (2013.01) [A61P 11/14 (2018.01)] 11 Claims
 
1. A method for treating chronic cough, the method comprising a step of administering an effective amount of a compound represented by Formula (I):

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof as an active ingredient to an individual in need of treatment of chronic cough,
wherein the effective amount of the active ingredient is a daily dose of 10 mg to 450 mg.