CPC A61B 5/14532 (2013.01) [A61B 5/0002 (2013.01); A61B 5/0004 (2013.01); A61B 5/0031 (2013.01); A61B 5/05 (2013.01); A61B 5/1411 (2013.01); A61B 5/1451 (2013.01); A61B 5/1473 (2013.01); A61B 5/1486 (2013.01); A61B 5/1495 (2013.01); A61B 5/14503 (2013.01); A61B 5/14507 (2013.01); A61B 5/14514 (2013.01); A61B 5/14546 (2013.01); A61B 5/14735 (2013.01); A61B 5/14865 (2013.01); A61B 5/6801 (2013.01); A61B 5/6833 (2013.01); A61B 5/6848 (2013.01); A61B 5/6849 (2013.01); A61B 5/68335 (2017.08); A61B 5/72 (2013.01); A61B 17/3468 (2013.01); A61B 5/14 (2013.01); A61B 5/145 (2013.01); A61B 5/1468 (2013.01); A61B 5/150022 (2013.01); A61B 2017/3492 (2013.01); A61B 2560/0223 (2013.01); A61B 2560/045 (2013.01); A61B 2560/063 (2013.01); A61B 2562/18 (2013.01); A61M 5/14244 (2013.01); A61M 5/1723 (2013.01); A61M 2005/1585 (2013.01); Y02A 90/10 (2018.01)] | 39 Claims |
1. A glucose monitoring system comprising:
a transcutaneous electrochemical glucose sensor comprising:
an in vivo portion configured to be inserted into a body of a human host, the in vivo portion having at least one electrode and a membrane containing glucose oxidase; and
an ex vivo portion configured to remain outside of the body of the host; and
at least one processor programmed to:
calculate an in vivo sensitivity for the transcutaneous electrochemical glucose sensor by converting an in vitro sensitivity associated with the transcutaneous electrochemical glucose sensor, wherein the in vitro sensitivity is obtained prior to insertion of the transcutaneous electrochemical glucose sensor, wherein the in vitro sensitivity is different from the in vivo sensitivity; and
determine an estimated glucose value based on an in vivo measurement from the in vivo portion of the transcutaneous electrochemical glucose sensor and the calculated in vivo sensitivity for the transcutaneous electrochemical glucose sensor,
wherein the in vivo sensitivity for the transcutaneous electrochemical glucose sensor is calculated without a need for a reference analyte measurement obtained after insertion of the in vivo portion of the transcutaneous electrochemical glucose sensor into the body of the human host.
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