US 12,208,081 B2
Tannin-containing gastrointestinal formulations and methods of use
Jess Dreher Reed, Madison, WI (US); Dhanansayan Shanmuganayagam, Madison, WI (US); Christian Gerald Krueger, Cambridge, WI (US); Kenneth Allan Kudsk, Madison, WI (US); Joseph Francis Pierre, Chicago, IL (US); Aaron F. Heneghan, Middleton, WI (US); and Rodrigo P. Feliciano, Düsseldorf (DE)
Assigned to Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed by Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed on Dec. 2, 2022, as Appl. No. 18/073,632.
Application 18/073,632 is a continuation of application No. 17/111,948, filed on Dec. 4, 2020, granted, now 11,559,511.
Application 17/111,948 is a continuation of application No. 16/102,844, filed on Aug. 14, 2018, granted, now 10,881,635, issued on Jan. 5, 2021.
Application 16/102,844 is a continuation of application No. 15/347,204, filed on Nov. 9, 2016, granted, now 10,105,345, issued on Oct. 23, 2018.
Application 15/347,204 is a continuation of application No. 14/152,267, filed on Jan. 10, 2014, granted, now 9,522,131, issued on Dec. 20, 2016.
Claims priority of provisional application 61/751,647, filed on Jan. 11, 2013.
Prior Publication US 2023/0114648 A1, Apr. 13, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/353 (2006.01); A23L 33/00 (2016.01); A23L 33/10 (2016.01); A23L 33/115 (2016.01); A23L 33/17 (2016.01); A61K 9/00 (2006.01)
CPC A61K 31/353 (2013.01) [A23L 33/10 (2016.08); A23L 33/115 (2016.08); A23L 33/17 (2016.08); A23L 33/40 (2016.08); A61K 9/0029 (2013.01); A23V 2002/00 (2013.01)] 23 Claims
OG exemplary drawing
 
1. An enteral or parenteral nutrition composition, comprising:
one or more nutrients comprising:
amino acids and/or polypeptides in an amount of at least 16% of total calories in the composition; and
carbohydrates in an amount of at least 25% of total calories in the composition; and
proanthocyanidins from one or more sources selected from the group consisting of cranberries, blueberries, grapes, sorghum, pomegranates, and pine,
wherein:
the composition is in the form of a powder and comprises the proanthocyanidins in an amount of at least 0.1 wt %, or the composition is in the form of a liquid and comprises the proanthocyanidins in an amount of at least 0.1 mg/L.