US 11,879,886 B2
System for viewing cell cultures under a microscope whilst applying
Moshe Giladi, Haifa (IL); Yoram Wasserman, Haifa (IL); Yoram Palti, Haifa (IL); Michael Krinitsky, Beer Sheva (IL); and Michael Shtotland, Haifa (IL)
Assigned to Novocure GmbH, Root (CH)
Filed by Novocure GmbH, Root (CH)
Filed on Jan. 3, 2023, as Appl. No. 18/092,742.
Application 18/092,742 is a division of application No. 15/872,318, filed on Jan. 16, 2018, granted, now 11,573,221.
Claims priority of provisional application 62/448,152, filed on Jan. 19, 2017.
Prior Publication US 2023/0141087 A1, May 11, 2023
Int. Cl. G01N 33/483 (2006.01); G01N 15/14 (2006.01); F21V 8/00 (2006.01); G01N 33/574 (2006.01); G02B 21/34 (2006.01); G02B 21/00 (2006.01)
CPC G01N 33/4836 (2013.01) [G01N 33/574 (2013.01); G02B 21/34 (2013.01); G02B 21/0088 (2013.01)] 8 Claims
OG exemplary drawing
 
1. An apparatus for optically observing a sample while applying electric fields to the sample, the apparatus comprising:
a fluid-tight container shaped and dimensioned for holding the sample, the container having a transparent bottom panel and ceramic sidewalls affixed to the transparent bottom panel, wherein the ceramic sidewalls have at least one outer surface;
a first electrode disposed at a first position on the at least one outer surface of the ceramic sidewalls;
a second electrode disposed at a second position on the at least one outer surface of the ceramic sidewalls, wherein the second position is opposite to the first position, so that application of an AC voltage between the first electrode and the second electrode induces an AC electric field through the sample in a first direction;
a third electrode disposed at a third position on the at least one outer surface of the ceramic sidewalls;
a fourth electrode disposed at a fourth position on the at least one outer surface of the ceramic sidewalls, wherein the fourth position is opposite to the third position, so that application of an AC voltage between the third electrode and the fourth electrode induces an AC electric field through the sample in a second direction;
a first electrical conductor arranged to route electricity between a first electrical terminal and the first electrode along a path that circumvents the transparent bottom panel;
a second electrical conductor arranged to route electricity between a second electrical terminal and the second electrode along a path that circumvents the transparent bottom panel;
a third electrical conductor arranged to route electricity between a third electrical terminal and the third electrode along a path that circumvents the transparent bottom panel; and
a fourth electrical conductor arranged to route electricity between a fourth electrical terminal and the fourth electrode along a path that circumvents the transparent bottom panel.