US 12,205,789 B1
Transmission electron microscopy with square beams
Eugene Yue Dao Chua, New York, NY (US); and Lambertus Michael Alink, Plainview, NY (US)
Assigned to New York Structural Biology Center, New York, NY (US)
Filed by New York Structural Biology Center, New York, NY (US)
Filed on Dec. 26, 2023, as Appl. No. 18/395,805.
Claims priority of provisional application 63/528,366, filed on Jul. 22, 2023.
Int. Cl. H01J 37/04 (2006.01); G01N 23/04 (2018.01)
CPC H01J 37/04 (2013.01) [G01N 23/04 (2013.01); G01N 2223/612 (2013.01); H01J 2237/0451 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A method of illuminating a sample in a Transmission Electron Microscope (TEM), the TEM having an illumination system comprising a set of optical lenses arranged in a column, and a camera, comprising:
configuring the illumination system with a non-circular beam shaping aperture;
during an illumination mode, illuminating a specimen using a non-circular shaped beam formed by the non-circular beam shaping aperture; and
tiling the non-circular shaped beam to maximize an area of the specimen imaged by the TEM;
wherein the non-circular beam is rotated with respect to an orientation of the camera.