US 12,205,492 B2
Compact dynamic simulator of the human gastrointestinal system
Angeline Riquelme, Santiago (CL); Sofía Estrugo, Santiago (CL); Francisca Villanueva, Santiago (CL); Rodrigo Muñoz-González, Santiago (CL); Ana Batista-Gonzalez, Santiago (CL); and Rodrigo A. Contreras, Santiago (CL)
Assigned to Notco Delaware, LLC, Santiago (CL)
Filed by NotCo Delaware, LLC, Santiago (CL)
Filed on Dec. 28, 2022, as Appl. No. 18/089,818.
Application 18/089,818 is a division of application No. 17/835,750, filed on Jun. 8, 2022, granted, now 11,580,883.
Claims priority of provisional application 63/303,148, filed on Jan. 26, 2022.
Prior Publication US 2023/0237934 A1, Jul. 27, 2023
Int. Cl. G09B 23/30 (2006.01)
CPC G09B 23/303 (2013.01) 20 Claims
OG exemplary drawing
 
1. An in vitro simulator of a human gastrointestinal system, comprising:
a thermoregulated bath maintained a specific temperature;
a first beaker positioned inside the thermoregulated bath, wherein an opening of the first beaker is covered by a first lid, wherein the first beaker includes a sieve configured to separate out particles smaller than a particular size;
a second beaker positioned inside the thermoregulated bath, wherein an opening of the second beaker is covered by a second lid;
a delivery channel passing through the first lid and the second lid, wherein the delivery channel includes a first channel end coupling with the sieve and a second channel end positioned inside the second beaker;
wherein the in vitro simulator mimics in vivo conditions of the human gastrointestinal system.