US 12,205,042 B2
Method and computing system for modelling a primate brain
Anthony Randal McIntosh, Toronto (CA); Jochen Mersmann, Stuttgart (DE); Viktor Jirsa, Aubagne (FR); and Petra Ritter, Berlin (DE)
Assigned to Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften e.V., Munich (DE); Baycrest Centre for Geriatric Care, Ontario (CA); Universite D'Aix Marseille, Marseilles (FR); Centre National De La Recherche Scientifique, Paris (FR); Institut National De La Sante Et De La Recherche Medicale, Paris (FR); and Codebox Computerdienste GmbH, Stuttgart (DE)
Filed by Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften e.V., Munich (DE); Baycrest Centre for Geriatric Care, Toronto (CA); CODEBOX COMPUTERDIENSTE GMBH, Stuttgart (DE); Universite D'Aix Marseille, Marseilles (FR); Centre National De La Recherche Scientifique, Paris (FR); and Institut National De La Sante Et De La Recherche Medicale, Paris (FR)
Filed on Jan. 23, 2023, as Appl. No. 18/158,182.
Application 18/158,182 is a continuation of application No. 16/278,370, filed on Feb. 18, 2019, granted, now 11,562,253.
Application 16/278,370 is a continuation of application No. 14/419,072, abandoned, previously published as PCT/IB2013/001707, filed on Aug. 2, 2013.
Claims priority of provisional application 61/678,950, filed on Aug. 2, 2012.
Prior Publication US 2023/0359906 A1, Nov. 9, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. G06N 3/10 (2006.01); G06N 3/04 (2023.01); G06N 3/049 (2023.01)
CPC G06N 3/10 (2013.01) [G06N 3/04 (2013.01); G06N 3/049 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A non-transitory computer readable medium encoded with non-transitory computer readable instructions for performing a process comprising:
accessing a computer-stored computer-simulation human whole brain model representing whole brain neural activity, the whole brain model divided into a plurality of user-modifiable anatomical regional brain subunit models respectively representing regional brain subunit neural activity and including a neural connectivity structure of the regional brain subunit within the regional brain subunit, to one or more other regional brain subunits of the whole brain model, or both; and
receiving user-modification of the human whole brain model or at least one of the regional brain subunit models to customize to a particular patient based at least in part on fitting at least one parameter of the human whole brain model or at least one of the regional brain subunit models to empirical intrinsic neural activity data measured from the particular patient.