Compositions and methods comprising protease variants
Ayrookaran J. Poulose, Belmont, CA (US); Joshua Roy Basler, Palo Alto, CA (US); Luis G. Cascao-Pereira, Redwood City, CA (US); James T. Kellis, Jr., Woodside, CA (US); Alexander Pisarchik, Marriottsville, MD (US); Daniel Esteban Torres Pazmino, Leiden (NL); and David A. Estell, San Mateo, CA (US)
Assigned to Danisco US Inc., Palo Alto, CA (US)
Filed by DANISCO US INC, Palo Alto, CA (US)
Filed on Dec. 10, 2021, as Appl. No. 17/547,287.
Application 14/225,292 is a division of application No. 12/963,930, filed on Dec. 9, 2010, granted, now 8,728,790.
Application 17/547,287 is a continuation of application No. 16/693,876, filed on Nov. 25, 2019, abandoned.
Application 16/693,876 is a continuation of application No. 14/843,833, filed on Sep. 2, 2015, abandoned.
Application 14/843,833 is a continuation of application No. 14/225,292, filed on Mar. 25, 2014, granted, now 9,157,052.
Claims priority of provisional application 61/392,373, filed on Oct. 12, 2010.
Claims priority of provisional application 61/285,127, filed on Dec. 9, 2009.
Prior Publication US 2022/0204959 A1, Jun. 30, 2022
1. An isolated protease variant of a parent protease, the protease variant comprising an amino acid sequence comprising the substitutions X101N-X128S-X217Q, wherein the protease variant has proteolytic activity and each amino acid position of the protease variant is numbered by correspondence to an amino acid position in the amino acid sequence of SEQ ID NO:2 as determined by alignment of the amino acid sequence of the protease variant with SEQ ID NO:2, and wherein the amino acid sequence has at least 85% sequence identity across its full length to the amino acid sequence of SEQ ID NO:2.
