US 12,202,801 B1
4-cyano-1-(2-oxo-2-(substituted phenyl) ethyl) pyridin-1-ium bromides as anti-tubercular agents
Katharigatta N. Venugopala, Al-Ahsa (SA); Melendran Pillay, Godihal (IN); Sandeep Chandrashekharappa, Lucknow (IN); and Mohamed A. Morsy, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Jan. 29, 2024, as Appl. No. 18/425,448.
Application 18/425,448 is a division of application No. 18/384,003, filed on Oct. 26, 2023.
Int. Cl. C07D 213/84 (2006.01); A61P 31/06 (2006.01)
CPC C07D 213/84 (2013.01) [A61P 31/06 (2018.01)] 12 Claims
 
1. A method of treating tuberculosis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
one or more R1 groups can be attached to the phenyl ring, wherein each R1 is independently selected from the group consisting of trihalomethyl, NO2, CN, and fluorine.