US 12,201,834 B2
Apparatuses and methods for transdermal electrical stimulation of nerves to modify or induce a cognitive state
Jonathan D. Charlesworth, Menlo Park, CA (US); Sumon K. Pal, Boston, MA (US); William J. Tyler, Tempe, AZ (US); Daniel Z. Wetmore, Brooklyn, NY (US); Isy Goldwasser, Los Gatos, CA (US); Alyssa M. Boasso, Brookline, MA (US); Hailey M. Mortimore, Boston, MA (US); and Rafal Piersiak, Los Gatos, CA (US)
Assigned to Thync Global, Inc., Los Gatos, CA (US)
Filed by Thync Global, Inc., Los Gatos, CA (US)
Filed on Jan. 31, 2022, as Appl. No. 17/649,517.
Application 17/649,517 is a continuation of application No. 16/417,625, filed on May 20, 2019, granted, now 11,235,148.
Application 16/417,625 is a continuation of application No. 15/384,249, filed on Dec. 19, 2016, granted, now 10,293,161, issued on May 21, 2019.
Claims priority of provisional application 62/281,326, filed on Jan. 21, 2016.
Claims priority of provisional application 62/279,992, filed on Jan. 18, 2016.
Claims priority of provisional application 62/269,975, filed on Dec. 19, 2015.
Claims priority of provisional application 62/269,104, filed on Dec. 18, 2015.
Prior Publication US 2022/0152389 A1, May 19, 2022
Int. Cl. A61N 1/36 (2006.01); A61N 1/04 (2006.01)
CPC A61N 1/36025 (2013.01) [A61N 1/0456 (2013.01); A61N 1/36034 (2017.08); A61N 1/0476 (2013.01); A61N 1/0492 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method of modifying a subject's sympathetic nervous system, the method comprising:
delivering a transdermal electrical stimulation between an anode at a first location on the subject's skin on the back of the subject's neck, and a cathode positioned at a second location on the subject's skin on the back of the subject's neck;
wherein the transdermal electrical stimulation between the anode and cathode is applied until the subject's sympathetic nervous system is suppressed,
wherein delivering the transdermal electrical stimulation comprises applying a first capacitive discharge current at an end of a positive-going pulse and/or applying a second capacitive discharge current at an end of a negative-going pulse, wherein the first and second capacitive discharge currents correspond to spikes in current.