US 12,201,710 B2
Hydrophilic silica/polymer blend
Luqing Qi, Midland, MI (US); Liang Chen, Sewickley, PA (US); Lu Bai, Novi, MI (US); Lyndsay M. Leal, Spring City, PA (US); David M. Meunier, Midland, MI (US); Yunshen Chen, Lexington, MA (US); and Fanwen Zeng, Audubon, PA (US)
Assigned to Dow Global Technologies LLC, Midland, MI (US); and Rohm and Haas Company, Collegeville, PA (US)
Appl. No. 17/601,111
Filed by Dow Global Technologies LLC, Midland, MI (US); and Rohm and Haas Company, Collegeville, PA (US)
PCT Filed Apr. 16, 2020, PCT No. PCT/US2020/028422
§ 371(c)(1), (2) Date Oct. 4, 2021,
PCT Pub. No. WO2020/223024, PCT Pub. Date Nov. 5, 2020.
Claims priority of provisional application 62/840,487, filed on Apr. 30, 2019.
Prior Publication US 2022/0160596 A1, May 26, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/25 (2006.01); A61K 8/37 (2006.01); A61K 8/81 (2006.01); A61K 8/86 (2006.01); A61Q 5/02 (2006.01); A61Q 19/10 (2006.01)
CPC A61K 8/25 (2013.01) [A61K 8/375 (2013.01); A61K 8/8147 (2013.01); A61K 8/86 (2013.01); A61Q 5/02 (2013.01); A61Q 19/10 (2013.01); A61K 2800/48 (2013.01)] 17 Claims
 
1. A hydrophilic silica/polymer blend comprising:
(a) a hydrophilic silica powder; and
(b) a thickening polymer powder, wherein the thickening polymer powder comprises:
(i) 79 to 95.74 wt %, based on weight of the thickening polymer powder, of structural units of C4-8 alkyl (meth)acrylate monomer;
(ii) 0.5 to 5 wt %, based on weight of the thickening polymer powder, of structural units of (meth)acrylic acid monomer;
(iii) 3.75 to 14 wt %, based on weight of the thickening polymer powder, of structural units of (methoxy) poly(ethylene glycol) (meth)acrylate monomer; and
(iv) 0.01 to 2 wt %, based on weight of the thickening polymer powder, of structural units of multiethylenically unsaturated monomer;
wherein the hydrophilic silica/polymer blend is a physical blend of the hydrophilic silica powder and the thickening polymer powder; and
wherein the weight ratio of hydrophilic silica powder to thickening polymer powder in the hydrophilic silica/polymer blend is 1:2 to 2:1.