US 12,201,646 B2
Hydrogel tablet for relieving alcoholism and protecting the liver as well as preparation process and application thereof
Zhang Hu, Zhanjiang (CN); Sitong Lu, Zhanjiang (CN); Songzhi Kong, Zhanjiang (CN); Sidong Li, Zhanjiang (CN); Lingyu Zhang, Zhanjiang (CN); Mingneng Liao, Zhanjiang (CN); Chengpeng Li, Zhanjiang (CN); and Yu Cheng, Zhanjiang (CN)
Assigned to GUANGDONG OCEAN UNIVERSITY, Zhanjiang (CN)
Appl. No. 17/277,673
Filed by GUANGDONG OCEAN UNIVERSITY, Zhanjiang (CN)
PCT Filed Nov. 20, 2020, PCT No. PCT/CN2020/130265
§ 371(c)(1), (2) Date Mar. 18, 2021,
PCT Pub. No. WO2021/104155, PCT Pub. Date Jun. 3, 2021.
Claims priority of application No. 201911174637.1 (CN), filed on Nov. 26, 2019.
Prior Publication US 2022/0040221 A1, Feb. 10, 2022
Int. Cl. A61K 31/722 (2006.01); A61K 9/20 (2006.01); A61K 31/734 (2006.01); A61K 33/10 (2006.01)
CPC A61K 31/722 (2013.01) [A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/205 (2013.01); A61K 9/2063 (2013.01); A61K 9/2072 (2013.01); A61K 9/2095 (2013.01); A61K 31/734 (2013.01); A61K 33/10 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A composition with the effects of relieving alcoholism and protecting the liver, comprising a powder particle including the following components on the basis of weight parts: 20-40 parts of chitosan, 25-55 parts of sodium alginate, 3-20 parts of gelatin, 1-10 parts of calcium carbonate and 0.05-0.5 parts of gallic acid;
wherein the powder particle comprises chitosan/sodium alginate shell-calcium carbonate core of a core-shell structure encapsulated with a layer gelatin membrane, wherein the chitosan/sodium alginate forms the shell and the calcium carbonate forms the core.