| CPC A61F 2/2415 (2013.01) [A61F 2/2418 (2013.01); B29C 33/34 (2013.01); B29C 33/38 (2013.01); B29C 33/42 (2013.01); B29C 35/02 (2013.01); B29C 35/16 (2013.01); B29C 37/0053 (2013.01); D01D 5/0007 (2013.01); D01D 5/0076 (2013.01); A61F 2/246 (2013.01); A61F 2/2466 (2013.01); A61L 27/34 (2013.01); A61L 2430/20 (2013.01)] | 13 Claims |
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1. A method of forming an electrospun prosthetic valve, the method comprising the steps of:
angularly adjusting a prosthetic valve mold to a first angle, the valve mold coupled to a first portion of a bracket, and a base coupled to a second portion of the bracket such that angularly adjusting the prosthetic valve mold comprises angularly adjusting the first portion of the bracket relative to the second portion of the bracket, the bracket comprising a locking mechanism operable between an unlocked configuration and a locked configuration, wherein in the unlocked conguration, the first portion of the bracket is angularly adjustable relative to the second portion of the bracket about a pivot joint to change the first angle between the valve mold and the base within a range between 0 degrees to 180 degrees, and in the locked configuration, the first portion of the bracket is non-movable relative to the second portion of the bracket,
rotating the prosthetic valve mold at a first rotational velocity;
depositing a first layer of a first plurality of electrospun fibers onto the prosthetic valve mold;
stopping the rotation of the prosthetic valve mold from the first rotational velocity;
positioning a frame radially outward of the first layer;
rotating the prosthetic valve mold including the first layer and the frame at a second rotational velocity;
depositing a second layer of a second plurality of electrospun fibers onto an outer surface of the frame and an outer surface of the first layer;
stopping the rotation of the prosthetic valve mold, and
processing the precursor electrospun prosthetic valve to form the electrospun prosthetic valve.
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