US 12,201,508 B2
Dynamic microvalve protection device
James E. Chomas, Denver, CO (US); Aravind Arepally, Atlanta, GA (US); Bryan M. Pinchuk, Miami, FL (US); and Leonard Pinchuk, Miami, FL (US)
Assigned to TriSalus Life Sciences, Inc., Westminster, CO (US)
Filed by TriSalus Life Sciences, Inc., Westminster, CO (US)
Filed on Sep. 21, 2020, as Appl. No. 17/027,667.
Application 17/027,667 is a continuation of application No. 15/804,839, filed on Nov. 6, 2017, granted, now 10,813,739.
Application 15/804,839 is a continuation of application No. 14/806,596, filed on Jul. 22, 2015, granted, now 9,808,332, issued on Nov. 7, 2017.
Application 14/806,596 is a continuation of application No. 13/306,105, filed on Nov. 29, 2011, granted, now 9,539,081, issued on Jan. 10, 2017.
Application 13/306,105 is a continuation in part of application No. 12/957,533, filed on Dec. 1, 2010, granted, now 8,696,698, issued on Apr. 15, 2014.
Application 12/957,533 is a continuation in part of application No. 12/829,565, filed on Jul. 2, 2010, granted, now 8,500,775, issued on Aug. 6, 2013.
Claims priority of provisional application 61/382,290, filed on Sep. 13, 2010.
Claims priority of provisional application 61/266,068, filed on Dec. 2, 2009.
Prior Publication US 2021/0000582 A1, Jan. 7, 2021
Int. Cl. A61F 2/01 (2006.01); A61B 17/12 (2006.01); A61F 2/24 (2006.01); A61M 25/00 (2006.01); A61B 17/00 (2006.01); A61B 17/22 (2006.01)
CPC A61F 2/013 (2013.01) [A61B 17/12186 (2013.01); A61F 2/0105 (2020.05); A61F 2/2412 (2013.01); A61F 2/2436 (2013.01); A61M 25/0075 (2013.01); A61B 17/00491 (2013.01); A61B 2017/22082 (2013.01); A61F 2/011 (2020.05); A61F 2002/016 (2013.01); A61F 2002/018 (2013.01); A61F 2230/0006 (2013.01); A61F 2230/0067 (2013.01); A61F 2230/0076 (2013.01); A61F 2230/008 (2013.01); A61M 2025/0004 (2013.01); A61M 25/005 (2013.01)] 17 Claims
OG exemplary drawing
 
1. An endovascular system for use in a vessel having a vessel wall during an intravascular procedure, comprising:
a) an inner catheter having a proximal end and a distal end;
b) an outer catheter having a proximal end and a distal end;
c) a handle system operably coupled to the proximal ends of the inner and outer catheters, the handle system including a first handle portion and a second handle portion movable relative to the first handle portion, the first handle portion coupled to the inner catheter and the second handle portion coupled to the outer catheter;
d) a microvalve coupled to the distal ends of the inner and outer catheters, the microvalve held in a radially-collapsed state for advancement within the vessel, and expandable from the radially-collapsed state into a radially-expanded state,
wherein the microvalve is dynamically movable within the vessel depending on a local fluid pressure about the microvalve such that,
when the fluid pressure is higher on a proximal side of the microvalve than on a distal side of the microvalve, the microvalve assumes a first diameter smaller than a diameter of the vessel such that blood flow about the valve is permitted, and
when the fluid pressure is higher on the distal side of the microvalve than on the proximal side of the microvalve, the microvalve assumes a second diameter relatively larger than the first diameter and in which the microvalve is adapted to contact the vessel wall;
wherein the handle system is operable to linearly displace the inner and outer catheters relative to each other to move the microvalve between the radially-collapsed state and the radially-expanded state; and
e) a visual indicator indicating an extent to which the microvalve is opened.