US 12,201,413 B2
Free breathing dynamic contrast enhanced (DCE) liver MR imaging
Hongyu An, St. Louis, MO (US); Ulugbek Kamilov, St. Louis, MO (US); Sihao Chen, St. Louis, MO (US); Cihat Eldeniz, St. Louis, MO (US); Weijie Gan, St. Louis, MO (US); Jiaming Liu, St. Louis, MO (US); and Tyler Fraum, St. Louis, MO (US)
Assigned to Washington University, St. Louis, MO (US)
Filed by Washington University, St. Louis, MO (US)
Filed on Mar. 1, 2023, as Appl. No. 18/176,876.
Prior Publication US 2024/0293039 A1, Sep. 5, 2024
Int. Cl. A61B 5/055 (2006.01)
CPC A61B 5/055 (2013.01) [G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for reconstructing dynamic contrast-enhanced (DCE) MR images comprising:
receiving a plurality of continuous free-breathing DCE images, the plurality of images obtained with a contrast;
sorting the images by identifying a respiratory phase associated with each of the continuous free-breathing DCE images;
reconstructing the plurality continuous free-breathing DCE images into a 4 D respiratory motion-resolved image;
obtaining 3D deformable motion vector fields (MVFs); and
utilizing a deep learning based motion transformation integrated forward-Fourier (DL-MOTIF) model and the 3D deformable MVFs to reconstruct the DCE MR images.