CPC C12P 17/182 (2013.01) [C12N 1/22 (2013.01); C12N 9/1018 (2013.01); C12N 9/88 (2013.01); C12P 7/6409 (2013.01); G01N 2333/91034 (2013.01)] | 27 Claims |
1. A recombinant yeast microorganism comprising one or more engineered metabolic pathways to convert a carbohydrate source to ethanol and a malonyl-CoA derived product, wherein the one or more engineered metabolic pathways comprises (a) the conversion of phosphoenolpyruvate to oxaloacetate by a phosphoenolpyruvate carboxykinase and (b) the conversion of oxaloacetate and acetyl-CoA to malonyl-CoA and pyruvate by a heterologous transcarboxylase Enzyme Commission Number 2.1.3.1; wherein the one or more engineered metabolic pathways further comprises heterologous pyruvate formate lyase.
|