US 11,873,505 B2
Compositions and methods for regulating production of a precursor protein
Bradley G. Thompson, Calgary (CA)
Assigned to Wyvern Pharmaceuticals Inc., Calgary (CA)
Filed by Wyvern Pharmaceuticals Inc., Calgary (CA)
Filed on Dec. 23, 2020, as Appl. No. 17/132,385.
Application 17/132,385 is a continuation of application No. 17/105,967, filed on Nov. 27, 2020.
Prior Publication US 2022/0170043 A1, Jun. 2, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/763 (2015.01); C12N 15/86 (2006.01); C07K 14/705 (2006.01)
CPC C12N 15/86 (2013.01) [C07K 14/705 (2013.01); C12N 2750/14141 (2013.01)] 3 Claims
 
1. A recombinant oncolytic virus vector (ROVV), the ROVV comprising an oncolytic virus containing:
a) a promotor, followed by:
b) a nucleotide sequence encoding a toll-like receptor 3 (TLR3) precursor protein, wherein the nucleotide sequence is SEQ ID No. 1.