US 11,872,202 B2
Pleuromutilin cinnamic acid ester compounds with activities against antibiotic-resistant infections
Chengyuan Liang, Xi'an (CN); Xiuding Yang, Xi'an (CN); Liang Xin, Xi'an (CN); Juan Xia, Xi'an (CN); Yuqing Zhao, Xi'an (CN); Jie Zhang, Xi'an (CN); Lei Tian, Xi'an (CN); Jingyi Li, Xi'an (CN); Shaojun Zhang, Xi'an (CN); and Qianqian Zhao, Xi'an (CN)
Assigned to SHAANXI UNIVERSITY OF SCIENCEAND TECHNOLOGY, Shaanxi (CN)
Filed by Chengyuan Liang, Xi'an (CN); Xiuding Yang, Xi'an (CN); Liang Xin, Xi'an (CN); Juan Xia, Xi'an (CN); Yuqing Zhao, Xi'an (CN); Jie Zhang, Xi'an (CN); Lei Tian, Xi'an (CN); Jingyi Li, Xi'an (CN); Shaojun Zhang, Xi'an (CN); and Qianqian Zhao, Xi'an (CN)
Filed on Mar. 15, 2022, as Appl. No. 17/695,741.
Claims priority of application No. 202111479806.X (CN), filed on Dec. 6, 2021.
Prior Publication US 2023/0172889 A1, Jun. 8, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/216 (2006.01); A61P 31/04 (2006.01)
CPC A61K 31/216 (2013.01) [A61P 31/04 (2018.01)] 2 Claims
 
1. A pleuromutilin cinnamic acid ester compound with activities against antibiotic-resistant infections having the following formula (I):

OG Complex Work Unit Chemistry
wherein R1, R2, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halogen, nitro, cyano, methoxy, trifluoromethyl, benzyloxy, aryl, imidazolidine, and dimethylamino.