CPC A61B 34/10 (2016.02) [A61B 5/0044 (2013.01); A61B 5/021 (2013.01); A61B 5/02007 (2013.01); A61B 5/02028 (2013.01); A61B 5/0263 (2013.01); A61B 6/032 (2013.01); A61B 6/504 (2013.01); A61B 6/507 (2013.01); A61B 6/5217 (2013.01); A61B 6/5247 (2013.01); G16H 10/60 (2018.01); G16H 30/40 (2018.01); G16H 50/50 (2018.01); A61B 2034/105 (2016.02); A61B 2034/108 (2016.02); A61B 2505/05 (2013.01); A61B 2576/023 (2013.01)] | 20 Claims |
1. A method of generating a coronary artery model comprising:
receiving patient-specific anatomical structure data and patient-specific physiological data, wherein the anatomical structure data comprises structural information about a patient's coronary arteries, and wherein the patient-specific physiological data comprises a continuously recorded blood pressure waveform from a non-invasive measurement;
generating, based at least in part on the anatomical structure data, an anatomical model of at least a portion of the patient's coronary arteries;
generating an inflow or an outflow waveform boundary condition for a computational fluid dynamics (CFD) simulation of blood flow in the anatomical model by:
(i) assigning the continuously recorded blood pressure waveform as the boundary condition, and
(ii) using the continuously recorded blood pressure waveform to model the boundary condition;
simulating blood flow in the anatomical model using CFD and the inflow or the outflow waveform boundary condition for the CFD simulation of blood flow; and
determining, based at least in part on the simulation, one or more hemodynamic parameters associated with the patient's coronary arteries,
thereby generating a coronary artery model.
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