CPC A61B 5/0071 (2013.01) [A61B 1/063 (2013.01); A61B 5/0084 (2013.01); A61B 5/4381 (2013.01); A61K 49/00 (2013.01); G01N 21/658 (2013.01); G01N 33/54346 (2013.01); G01N 33/574 (2013.01); G01N 33/57434 (2013.01); B82Y 15/00 (2013.01)] | 21 Claims |
1. A Surface-Enhanced Raman Spectroscopy (SERS) reporter nanoplex comprising a compound of the formula:
wherein:
L is a linker; and
Ⓢ is a SERS tag;
wherein the SERS tag comprises at least one Raman reporter molecule disposed between a gold nanostar and a silica layer on its surface, wherein the at least one Raman reporter molecule is selected from 4-nitrothiophenol (NTP), 4-mercaptobenzoic acid (MBA), malachite green isothiocyanate (MGITC), and rhodamine B isothiocyanate (RBITC).
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