US 12,194,264 B2
Magnetomechanic triggering of payload release from miniaturized devices
Michael Shpigelmacher, Los Angeles, CA (US); Alex Kiselyov, San Diego, CA (US); Suehyun Cho, Los Angeles, CA (US); and Hovhannes Sargsyan, North Hollywood, CA (US)
Assigned to BIONAUT LABS LTD., (IL)
Appl. No. 17/289,682
Filed by BIONAUT LABS LTD., Herzliya (IL)
PCT Filed Oct. 31, 2019, PCT No. PCT/US2019/059135
§ 371(c)(1), (2) Date Apr. 28, 2021,
PCT Pub. No. WO2020/092750, PCT Pub. Date May 7, 2020.
Claims priority of provisional application 62/754,998, filed on Nov. 2, 2018.
Prior Publication US 2021/0402161 A1, Dec. 30, 2021
Int. Cl. A61K 9/00 (2006.01); A61M 31/00 (2006.01); A61M 37/00 (2006.01)
CPC A61M 37/0069 (2013.01) [A61K 9/0009 (2013.01); A61K 9/0024 (2013.01); A61K 9/0097 (2013.01); A61M 31/002 (2013.01)] 24 Claims
OG exemplary drawing
 
1. A device for implanting in a biological tissue to release a functional material in said tissue or in another tissue, the device comprising:
a cavity having an opening through an external surface of said device;
a matrix comprising a functional material, wherein the matrix is contained within said cavity; and
a magnetic component contained and moveable in said cavity, and is arranged so that, when a magnet trigger is applied, the magnetic component extrudes the matrix through the opening of cavity to be released into the tissue, and
wherein the cavity is sealed by or covered with a flexible seal, which opens when the matrix is extruded by the magnetic component.