US 11,867,699 B2
Detecting an analyte
Chengzhong Yu, St. Lucia (AU); Meihua Yu, Chapel Hill (AU); Chang Lei, Sinnamon Park (AU); and Mohammad Kalantari, Annerley Queensland (AU)
Assigned to THE UNIVERSITY OF QUEENSLAND, St Lucia (AU)
Appl. No. 16/308,219
Filed by THE UNIVERSITY OF QUEENSLAND, St. Lucia (AU)
PCT Filed Jun. 12, 2017, PCT No. PCT/AU2017/050584
§ 371(c)(1), (2) Date Dec. 7, 2018,
PCT Pub. No. WO2017/210754, PCT Pub. Date Dec. 14, 2017.
Claims priority of application No. 2016902275 (AU), filed on Jun. 10, 2016.
Prior Publication US 2019/0265247 A1, Aug. 29, 2019
Int. Cl. G01N 33/58 (2006.01); C01B 33/113 (2006.01); G01N 33/543 (2006.01); G01N 21/64 (2006.01); C01B 32/15 (2017.01); C01B 37/02 (2006.01); C01B 33/18 (2006.01); B82Y 15/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01)
CPC G01N 33/588 (2013.01) [C01B 32/15 (2017.08); C01B 33/113 (2013.01); C01B 33/18 (2013.01); C01B 33/185 (2013.01); C01B 37/02 (2013.01); G01N 21/64 (2013.01); G01N 33/54346 (2013.01); G01N 33/587 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C01P 2004/62 (2013.01); C12Y 111/01007 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method for detecting an analyte in a sample, including a step of contacting said analyte with a nanoparticle to facilitate binding thereto, wherein the nanoparticle comprises:
(i) a core;
(ii) pores extending radially from said core and being defined by spaces between an array of dendritic spikes radiating outwardly from a surface of the core, wherein the pores have an average pore size of between about 10 nm and about 20 nm;
(iii) a binding agent for binding the analyte; and
(iv) a detection agent immobilized within said pores;
to thereby detect said analyte.