CPC C07K 16/2803 (2013.01) [A61P 29/00 (2018.01); G01N 33/6854 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01)] | 6 Claims |
1. A method for analyzing the presence or absence of inflammation in a tissue in a subject, comprising determining the presence of secreted CHL1 protein in the tissue, a body fluid, or excrement obtained from the subject by using an antibody or an antigen-binding fragment thereof that binds to secreted CHL1 protein,
wherein the antibody and the fragment has a heavy chain variable region having heavy chain CDR1 having the amino acid sequence set forth in SEQ ID NO: 1, heavy chain CDR2 having the amino acid sequence set forth in SEQ ID NO: 2 and heavy chain CDR3 having the amino acid sequence set forth in SEQ ID NO: 3, and a light chain variable region having light chain CDR1 having the amino acid sequence set forth in SEQ ID NO: 5, light chain CDR2 having the amino acid sequence set forth in SEQ ID NO: 6 and light chain CDR3 having the amino acid sequence set forth in SEQ ID NO: 7.
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