US 11,864,574 B1
Encapsulated polyphenolic compounds
Marwa Ezz El-Din Ibrahim, Al-Ahsa (SA); and Randah Miqbil Alqurashi, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Jun. 20, 2023, as Appl. No. 18/203,444.
Int. Cl. A23L 3/44 (2006.01); A23L 29/00 (2016.01); A23L 19/00 (2016.01)
CPC A23L 3/44 (2013.01) [A23L 19/07 (2016.08); A23L 29/035 (2016.08)] 12 Claims
OG exemplary drawing
 
1. A method of making an encapsulated polyphenolic composition, comprising:
(a) mixing a first phenolic extract derived from pomegranate peels with a dehydrated orange peel powder to obtain a first mixture;
(b) freeze drying the first mixture to obtain a first encapsulated powder;
(c) mixing the first encapsulated powder with a second phenolic extract derived from pomegranate peels to obtain a second mixture;
(d) freeze drying the second mixture to obtain a second encapsulated powder comprising the encapsulated polyphenolic composition;
wherein the first phenolic extract derived from pomegranate peels and the second phenolic extract derived from pomegranate peels are the same phenolic extract derived from pomegranate peels;
wherein the phenolic extract derived from pomegranate peels is obtained by a process comprising:
(e) peeling a pomegranate to obtain pomegranate peels;
(f) drying the pomegranate peels to obtain dried pomegranate peels;
(g) grinding the dried pomegranate peels to obtain ground pomegranate peels;
(h) extracting the phenolic extract derived from pomegranate peels by soaking the ground pomegranate peels in methanol;
wherein the method of making an encapsulated polyphenolic composition further comprises:
(i) storing the ground pomegranate peels soaked in methanol in a refrigerator for multiple days with daily shaking;
(j) following the storing, percolating the ground pomegranate peels soaked in methanol multiple times until complete exhaustion;
(k) following the percolating, centrifuging the ground pomegranate peels soaked in methanol to obtain a methanolic extract; and
(l) concentrating the methanolic extract by evaporating every 100 ml of methanol to 20 ml of methanol to obtain the phenolic extract derived from pomegranate peels.