US 10,891,313 B2
Systems and methods for sensory and cognitive profiling
Todd Prentice Coleman, La Jolla, CA (US); Rui Ma, San Diego, CA (US); Sanggyun Kim, San Diego, CA (US); Cheolsoo Park, San Diego, CA (US); Ricardo Gil Da Costa, San Diego, CA (US); Raynard Fung, La Jolla, CA (US); and Diego Mesa, La Jolla, CA (US)
Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US); and THE SALK INSTITUTE FOR BIOLOGICAL STUDIES, La Jolla, CA (US)
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US); and THE SALK INSTITUTE FOR BIOLOGICAL STUDIES, La Jolla, CA (US)
Filed on Jan. 24, 2018, as Appl. No. 15/879,396.
Application 15/879,396 is a continuation of application No. 14/431,734, granted, now 9,886,493, previously published as PCT/US2013/062491, filed on Sep. 27, 2013.
Claims priority of provisional application 61/707,613, filed on Sep. 28, 2012.
Prior Publication US 2018/0285442 A1, Oct. 4, 2018
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/0484 (2006.01); G06F 16/28 (2019.01); G06F 16/2457 (2019.01); A61B 5/0482 (2006.01); G16H 10/20 (2018.01); A61B 5/00 (2006.01); A61B 5/0488 (2006.01); A61B 5/16 (2006.01)
CPC G06F 16/285 (2019.01) [A61B 5/0482 (2013.01); A61B 5/0484 (2013.01); G06F 16/24578 (2019.01); G16H 10/20 (2018.01); A61B 5/0488 (2013.01); A61B 5/04842 (2013.01); A61B 5/04845 (2013.01); A61B 5/04847 (2013.01); A61B 5/165 (2013.01); A61B 5/167 (2013.01); A61B 5/168 (2013.01); A61B 5/4011 (2013.01); A61B 5/4017 (2013.01); A61B 5/6814 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A portable system for measuring brain waves to determine cerebral ability, comprising:
a wearable sensor device including a flexible substrate, electrodes on the flexible substrate, and a wireless transmitter in electrical communication with the electrodes, the wearable sensor device configured to record electrophysiological signals of a subject and transmit the recorded electrophysiological signals by the wireless transmitter to an external computing device, wherein the wearable sensor device is operable to detect the electrophysiological signals exhibited by the subject before, during, and after a presentation of a sequence of stimuli to the subject, the sequence of stimuli based on a cognitive-sensory profile category from among one or more of a cognitive performance profile, a sensory performance profile, or a cognitive and sensory performance profile;
a mobile communications device in wireless communication with the wearable sensor device, the mobile communications device including a data processing unit, including a processor and memory, and a stimulus generation unit, wherein the data processing unit is operable to process the electrophysiological signals as physiological data to generate an information set including one or more quantitative values associated with the cognitive-sensory profile category, and the stimulus generation unit is operable to produce the sequence of stimuli that is presented to the subject by a display in communication with the data processing unit; and
a brain-machine interface to produce a modified sequence of stimuli by adaptively modifying the sequence of stimuli during an on-going presentation of the stimuli to the subject, wherein the modified sequence of stimuli is based on data associated with or derived from the generated information set,
wherein the information set is generated by the data processing unit without requiring a behavioral response by the subject to the sequence of stimuli.