US 10,888,527 B2
Stable solid pharmaceutical formulations containing 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cylcohexanedione
Chiara Conti, Vigolo Marchese (IT); Salvatore Agostino Giammillari, Rozzano (IT); and Giuseppe Maccari, Voghera (IT)
Assigned to DIPHARMA S.A., Chiasso (CH)
Appl. No. 15/766,665
Filed by Dipharma S.A., Chiasso (CH)
PCT Filed Feb. 9, 2017, PCT No. PCT/EP2017/052805
§ 371(c)(1), (2) Date Apr. 6, 2018,
PCT Pub. No. WO2017/137468, PCT Pub. Date Aug. 17, 2017.
Claims priority of application No. UB2016A0650 (IT), filed on Feb. 11, 2016.
Prior Publication US 2019/0160014 A1, May 30, 2019
Int. Cl. A61K 31/135 (2006.01); A61K 9/48 (2006.01); A61K 31/122 (2006.01)
CPC A61K 9/4866 (2013.01) [A61K 9/4825 (2013.01); A61K 9/4858 (2013.01); A61K 31/122 (2013.01)] 20 Claims
 
1. A stable solid pharmaceutical formulation comprising 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione as a pharmaceutically active ingredient, pregelatinized starch and stearic acid.