US 10,888,424 B2
Prosthetic mitral valve coaptation enhancement device
Maximilian Kuetting, Boeblingen (DE); Emilia Kawa, Hechingen (DE); and Marcos Centola, Hechingen (DE)
Assigned to MEDIRA AG, Muri (CH)
Filed by NVT AG, Muri (CH)
Filed on Dec. 21, 2016, as Appl. No. 15/387,336.
Claims priority of application No. 15202121 (EP), filed on Dec. 22, 2015.
Prior Publication US 2017/0172737 A1, Jun. 22, 2017
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/246 (2013.01) [A61F 2/2418 (2013.01); A61F 2/2448 (2013.01); A61F 2/2457 (2013.01); A61F 2220/0008 (2013.01); A61F 2220/0016 (2013.01); A61F 2230/0069 (2013.01); A61F 2250/006 (2013.01); A61F 2250/0018 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A prosthetic mitral valve coaptation enhancement device for implanting at the native mitral valve region of a heart, wherein the native mitral valve, having a native annulus and native valve leaflets, can still perform a closing movement, and wherein the prosthetic mitral valve coaptation enhancement device comprising:
a main body consisting of a stentframe and a valve element attached thereto, the main body comprising a length and a lumen being defined by a proximal end and a distal end, and configured for placement within the native mitral valve region of the heart, the stentframe being radially compressible to a radially compressed state for delivery into the heart and self-expandable from the compressed state to a radially expanded state, wherein the main body has a sealing section and a valve-bearing section, the valve-bearing section carrying a valve element:
wherein
the shape of the sealing section of the main body, when compressed by the native valve leaflets, has a form that is adapted to the coaptation zone of the native mitral valve during systole, that
in the sealing section of the main body, the radial rigidity of the stentframe is lower than the radial rigidity of the valve-bearing section; and that
the sealing section of the main body is configured such that it is smaller than the native annulus of the heart into which the prosthetic mitral valve coaptation enhancement device is to be implanted and such that it contacts the native leaflets only during systole, thereby sealing the mitral annulus during systole and permitting filling of the ventricle through and alongside the prosthetic mitral valve coaptation enhancement device during diastole, thereby minimizing the gradient between the left atrium and ventricle;
and that the prosthetic mitral valve coaptation enhancement device further comprises at least one substantially rigid anchoring element, which anchoring element is coupled to the main body and is capable to anchor the main body within the native mitral valve region of a heart.