US 10,888,407 B2
Method for forming a multi-layer construct
Seth Dylan McCullen, Greenville, SC (US); Clayton Joseph Culbreath, Anderson, SC (US); Michael Aaron Vaughn, Anderson, SC (US); and Michael Scott Taylor, Anderson, SC (US)
Assigned to POLY-MED, INC., Anderson, SC (US)
Appl. No. 16/60,856
Filed by POLY-MED, INC., Anderson, SC (US)
PCT Filed Dec. 10, 2016, PCT No. PCT/US2016/000125
§ 371(c)(1), (2) Date Jun. 8, 2018,
PCT Pub. No. WO2017/099820, PCT Pub. Date Jun. 15, 2017.
Claims priority of provisional application 62/266,008, filed on Dec. 11, 2015.
Prior Publication US 2019/0000602 A1, Jan. 3, 2019
Int. Cl. B29C 41/24 (2006.01); B29C 41/26 (2006.01); B29C 41/32 (2006.01); B32B 5/24 (2006.01); A61F 2/00 (2006.01); A61L 27/00 (2006.01); D01D 5/00 (2006.01); A61L 27/58 (2006.01); B29L 31/00 (2006.01)
CPC A61F 2/0063 (2013.01) [A61L 27/00 (2013.01); A61L 27/58 (2013.01); D01D 5/0038 (2013.01); D01D 5/0076 (2013.01); D01D 5/0084 (2013.01); A61F 2210/0004 (2013.01); A61F 2240/001 (2013.01); A61F 2250/003 (2013.01); A61F 2250/0039 (2013.01); B29L 2031/753 (2013.01); B29L 2031/7532 (2013.01); B29L 2031/7534 (2013.01); B32B 2250/03 (2013.01); D10B 2509/06 (2013.01); D10B 2509/08 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A method for forming a multilayer construct, the method comprising:
a) providing an elastomeric base layer comprising a first synthetic polymer;
b) using an electrospinning technique to apply a first solution comprising the first synthetic polymer to the base layer, to provide a first fibrous layer which is elastomeric and directly adjoins the base layer;
c) using an electrospinning technique to apply a second solution comprising a second synthetic polymer to the first fibrous layer, to provide a second fibrous layer which directly adjoins the first fibrous layer;
wherein the first and second fibrous layers have non-identical properties in terms of average diameter of the fibers contained therein such that the fibers of the first fibrous layer have an average diameter which is greater than an average diameter of the fibers of the second fibrous layer.