US 12,191,133 B2
Mass spectrometry method for identifying and/or authenticating a sample
Frank Jochen Dieterle, Binningen (CH); Timm Fabian Manfred Hettich, Freiburg (DE); Christian Berchtold, Rheinfelden (CH); Gotz Schlotterbeck, Efringer-Kirchen (DE); and Markus Ehrat, Magden (CH)
Assigned to ORVINUM AG, Magden (CH)
Appl. No. 17/610,010
Filed by ORVINUM AG, Magden (CH)
PCT Filed May 8, 2020, PCT No. PCT/EP2020/062869
§ 371(c)(1), (2) Date Nov. 9, 2021,
PCT Pub. No. WO2020/229346, PCT Pub. Date Nov. 19, 2020.
Claims priority of application No. 19173824 (EP), filed on May 10, 2019.
Prior Publication US 2022/0199389 A1, Jun. 23, 2022
Int. Cl. H01J 49/36 (2006.01); H01J 49/00 (2006.01); H01J 49/16 (2006.01); G01N 33/14 (2006.01); G01N 33/483 (2006.01); G01N 33/49 (2006.01); G01N 33/493 (2006.01)
CPC H01J 49/165 (2013.01) [H01J 49/0036 (2013.01); G01N 33/146 (2013.01); G01N 33/4833 (2013.01); G01N 33/49 (2013.01); G01N 33/493 (2013.01)] 27 Claims
OG exemplary drawing
 
1. A method for identifying and/or authenticating a sample, wherein the method comprises the steps of:
(i) adding at least one compound to the sample, wherein the at least one compound has a variable ionization;
(ii) obtaining a mass spectrum of the at least one compound and determining a level of the at least one compound after addition to the sample;
(iii) comparing the level of the at least one compound determined in (ii) to a reference level, wherein the reference level is a level of the same compound determined after addition to a reference sample; and
(iv) identifying the sample based on the comparison in step (iii) and the effect of the sample on the level of the at least one compound.